The former EHF Champions League winners from 2001/02, HC Gjorche Petrov-WHC Skopje, came extremely close to mounting a full comeback in the tie against Höörs at home, but fell short by a single goal, with the Swedish club securing progress to qualification round 3. It was not as dramatic in Spain, as Bera Bera and Sport Lisboa e Benfica drew, with the Spanish champions going through due to their first leg win.

Vác, JDA Bourgogne Dijon Handball, KPR Gminy Kobierzyce and SCM Ramnicu Valcea all secured second wins in their ties, while HSG Blomberg-Lippe joined them despite the loss to SU ZRK Crvena Zvezda in Belgrade.