The first leg of the EHF European Cup Women 2025/26 quarter-finals opens with just two duels this weekend, as the other two ties will be carried out as double-headers next week. In an all-Spanish clash, Club Balonmán Atlético Guardes host ATTICGO Bm Elche on Saturday, before Turkish side Bursa Büyüksehir BSK take on Greek side A.C. PAOK in Türkiye the following day.